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Sleep patterns in the Lennox-Gastaut syndrome

Florence Miller Neuropediatric Diagnostic Unit and Sleep Diwrder Laboratory, Bikur Cholim Hospital, Jerusalem, Israel.

Serial polysomnograms were performed on 11 children with primary Lennox-Gastaut syndrome (LGS), 6 control children with other seizure disorders, and 12 who were developmentally normal. Five LGS chidren had abnormal polysomnograms with either complete absence or marked reduction of REM sleep; the other six LGS children had only a mild reduction of REM sleep. The percentage of REM in LGS children was less than in the controls with other seizure disorders (p < 0.05) or the normal children (p < 0.005). The scatter of REM percentages in LGS may imply heterogeneity of the syndrome, perhaps related to the severity of brainstem dysfunction or neurochemical derangement.

Address correspondence and reprint requests to Dr. Amir, Bikur Cholim Hospital, 5 Strauss Street, Jerusalem, Israel.

Accepted for publication January 14, 1986.

This article has been cited by other articles:

				J. F. Donat and F. S. Wright Review Article: Sleep, Epilepsy, and the EEG in Infancy and Childhood J Child Neurol, April 1, 1989; 4(2): 84 - 94. [Abstract] [PDF]