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Total body irradiation not effective in inclusion body myositis

Departments of Neurology (Dr. Kelly, Ms. Andres, and Dr. Munsat), Therapeutic Radiology (Dr. Madoc-Jones), and Pathology (Dr. Adelman), Tufts-New England Medical Center, Boston, MA.

Four patients with inclusion body myositis were treated with 150 rad of total body irradiation given in 5 weeks. One patient responded subjectively and transiently, but no patient showed clear benefit. This treatment is not recommended for inclusion body myositis.

Address correspondence and reprint requests to Dr. Kelly, Department of Neurology, Tufts-New England Medical Center, 171 Harrison Avenue, Boston, MA 02111.

Supported in part by funds from the Muscular Dystrophy Association.

Accepted for publication December 27, 1985.

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