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NEUROLOGY 1987;37:503
© 1987 American Academy of Neurology

Stroke in the Lehigh Valley

Risk factors for recurrent stroke

M. Alter, MD, PhD, E. Sobel, PhD, R. L. McCoy, MD, M. E. Francis, ScD, Z. Davanipour, DVM, PhD, F. Shofer, PhD, L. P. Levitt, MD and E. F. Meehan, MPH

Neuroepidemiology Section, Department of Neurology (Drs. Alter, Sobel, Francis, Davanipour, and Shofer), Temple University School of Medicine, Philadelphia; and the Lehigh Valley Stroke Program (Drs. McCoy and Levitt. and Mr. Meehan), Allentown, PA.

Age-specific risk of recurrent stroke for various risk factors, calculated independently, was estimated using the first year of data from the Lehigh Valley Stroke Register. The register is based on a population of more than one-half million. Among the risk factors examined, the highest overall risk of recurrent stroke, 41.4, occurred with a history of at least one transient ischemic attack (TIA). After myocardial infarction (MI), the relative risk of a recurrent stroke was 8.0, while with all other heart diseases combined it was 8.4. With diabetes, the relative risk of a recurrent stroke was 5.6; with hypertension, it was 4.5. The relative risk increased with age after TIA and MI, but not for other heart disease, diabetes, and hypertension, except in the 85 + year-old age group.

Address correspondence and reprint requests to Dr. Alter, Department of Neurology, Temple University School of Medicine, Philadelphia, PA 19140.

Supported in part by the Dorothy Rider Pool Trust, Allentown, PA, and the National Institutes of Health, Grant No. T-32 NS07256–02.

Received January 31, 1985. Accepted for publication in final form July 3, 1986.




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