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NEUROLOGY 1987;37:577
© 1987 American Academy of Neurology

An epileptic syndrome caused by mesial frontal lobe seizure foci

K. Waterman, S. J. Purves, B. Kosaka, E. Strauss and J. A. Wada

Divisions of Neurological Sciences and Neurology, Health Sciences Center Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

We describe an epileptic syndrome of bilaterally coordinated limb movements, axial movements, vocalization, and nonmasticatory oral activity. EEG and physiologic evidence indicates the syndrome is caused by ictal discharge in the mesial frontal lobes. Two of 12 patients were not helped by anterior temporal lobectomy, and 3 others improved after section of the anterior two-thirds of the corpus callosum.

Address correspondence and reprint requests to Dr. Wada, Divisions of Neurosciences and Neurology, Health Sciences Center Hospital, University of British Columbia, Vancouver, British Columbia V6T 2A1, Canada.

Supported by grants to Dr. J.A. Wada from the Medical Research Council of Canada, the Woodward Foundation, and the Vancouver Society for Epilepsy Research, and to Dr. E. Strauss from the Medical Research Council of Canada.

Presented in part to the American Epilepsy Society, San Francisco, 1984.

Received November 5, 1985. Accepted for publication in final form July 18, 1986.




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