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NEUROLOGY 1987;37:733
© 1987 American Academy of Neurology

Transient global amnesia

Clinical characteristics and prognosis

J. W. Miller, MD, PhD, R. C. Petersen, MD, PhD, E. J. Metter, MD, C. H. Millikan, MD and T. Yanagihara, MD

Department of Neurology, Mayo Chic and Mayo Foundation, Rochester, MN.

We studied the clinical characteristics of transient global amnesia (TGA) in 277 patients with an average follow-up of 80 months. The syndrome occurred most frequently after age 50. There was a history of migraine in 14.1% and cerebrovascular diseases in 11.2% of patients, but these conditions were usually not temporally linked to TGA. Characteristic antecedent events and activity such as exertion existed in 33.4%. The incidence of TGA was 5.2 per 100,000 per year in Rochester, MN. Although 23.8% of the patients had recurrent episodes, they were not at increased risk for subsequent stroke.

Address correspondence and reprint requesta to Dr. Yanagihara, Department of Neurology, Mayo Clinic, Rochester, MN 55905.

Supported in part by the Mayo Cerebrovascular Clinical Research Center grant from NINCDS (NS06663).

Presented in part at the thirty-sixth annual meeting of the American Academy of Neurology, Boston, MA, April 1984.

Received April 4, 1986. Accepted for publication in final form August 27, 1986.




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