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NEUROLOGY 1987;37:837
© 1987 American Academy of Neurology

Guillain-Barré syndrome

Quantitative measurement of plasma exchange therapy

Markus Färkkilä, MD, Esko Kinnunen, MD, Erkki Haapanen, MD and Matti Iivanainen, MD

Department of Neurology and Intensive Care Unit, University Hospital, Helsinki, Finland.

A prospective, controlled study with quantitative measurement of hand muscle-force for plasma exchange treatment in acute Guillain-Barré polyradiculitis was done. Of the 29 patients with severe symptoms, every second patient was selected to the plasma exchange group and all others to the control group. The muscle forces increased and CSF protein decreased significantly more in the plasma exchange group than in the control group, but there were no differences in hospitalization or recovery periods.

Address correspondence and reprint requests to Dr. Fäkkilä, Department of Neurology and Intensive Care Unit, University Hospital, Haartmaninkatu 4, 00290 Helsinki, Finland.

This work was financially supported by Paulo Foundation, Helsinki.

Received December 20, 1985. Accepted for publication in find form August 15, 1986.




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