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NEUROLOGY 1987;37:868
© 1987 American Academy of Neurology

Idiopathic normal pressure hydrocephalus and systemic hypertension

Neill R. Graff-Radford, MB, BCh, MRCP (UK) and John C. Godersky, MD

Departments of Neurology (Division of Behavioral Neurology) (Dr. Graff-Radford) and Surgery (Division of Neurosurgery) (Dr. Godersky), University of Iowa College of Medicine, Iowa City, IA.

Nineteen patients with idiopathic normal pressure hydrocephalus (NPH) were treated with intraventricular shunts. Ten of the 14 who improved and 14 of the total group had systemic hypertension. The prevalence of hypertension in both the improved and whole NPH groups was significantly greater than in a control group with dementia (N = 122) and the published prevalence of hypertension in the US population for this age group. Four possible mechanisms for this association are discussed.

Address correspondence and reprint requests to Dr. Graff-Radford, Department of Neurology. University of Iowa Hospitals & Clinics, Iowa City, IA 52242.

Received July 7, 1986. Accepted for publication in final form August 28, 1986.




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