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NEUROLOGY 1987;37:878
© 1987 American Academy of Neurology

Neurosarcoidosis

Cerebrospinal fluid lymphocyte subpopulations

B. J. Stern, MD, D. E. Griffin, MD, PhD, R. A. Luke, MD, A. Krumholz, MD and C. J. Johns, MD

Division of Neurology (Drs. Stern and Knunholz), Sinai Hospital of Baltimore, and the Departments of Neurology (Drs. Stern, Griffin, and Krumholz) and Medicine (Drs. Griffin, Luke, and Johns), The Johns Hopkina Hospital and University, Baltimore, MD.

CSF lymphocyte subpopulations of eight patients with neurosarcoidosis were examined. CSF or CT was abnormal in all. The CSF T4/T8 (helper/suppressor) ratio was elevated at 6.8 and 7.6 in two patients; in one, there were only CSF T4 cells. The ratio was normal in five patients.

Address correspondence and reprint requests to Dr. Stern, Division of Neurology, Sinai Hospital of Baltimore, Baltimore, MD 21215.

Presented in part at the thirty-seventh annual meeting of the American Academy of Neurology, Dallas, TX, April 1985.

Supported in part by USPHS grant NSZ1916.

Received December 17, 1985. Accepted for publication in final form September 5, 1986.




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