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Department of Neurology, Hadassah University Hospital, Jerusalem, Israel.
We studied various forms of dystonia associated with Parkinson's disease (PD) in 207 patients who were on levodopa therapy for more than 1 year. Dystonia, sometimes more than one type, occurred in 63 (30%). In five patients, dystonia preceded initiation of treatment. Fifteen patients had peak-dose dystonia, 33 had early-morning dystonia, and 20 had "off-period" dystonia. The different clinical features of the dystonias are presented and compared. Findings indicate that dystonia is a frequent feature of levodopa-treated PD patients.
Address correspondence and reprint requests to Dr. Kidron, Department of Neurology, Hadassah University Hospital, PO Box 12000, Jerusalem, 91 120, Israel.
Received July 1, 1986. Accepted for publication in final form September 19, 1986.
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