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Department of Neurology, UCLA School of Medicine, Los Angeles, C A.
Fifteen undemented patients with Parkinson's disease (PD) and 15 age-matched controls were given a battery of tests to assess sensorimotor integration in the arms. PD patients made more errors (p < 0.01) than controls, particularly in tests of proprioception. Age was not related to errors. Compared with controls, two-point discrimination thresholds were significantly higher (p <0.02) on the index finger of PD patients, but not on the forearm. Results confirm the sensorimotor deficits found earlier in an orofacial study, and imply that PD involves a generalized dysfunction of sensorimotor integration and proprioception, probably a result of impaired basal ganglia function in processing and integrating sensory input to organize and guide movement.
Address correspondence and reprint requests to Dr. Markham, Department of Neurology, UCLA School of Medicine, Reed Neurological Research Center, Los Angles, CA 90024.
Supported in part by donations from Ma. Heidi Fisher.
Received July 21, 1986. Accepted for publication in final form September 19, 1986.
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