HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Kushner, M. J. Articles by Reivich, M. Search for Related Content PubMed PubMed Citation Articles by Kushner, M. J. Articles by Reivich, M.

Cerebral metabolism and patterned visual Stimulation

A positron emission tomographic study of the human visual cortex

Cerebrovascular Research Center, Departments of Neurology (Dr. Kushner, Mr. Rosen, Mr. Dann, and Drs. Fazekas, Bosley, Greenberg, and Reivich), Anatomy (Dr. Rosenquist), and Radiology (Dr. Alavi), University of Pennsylvania, Philadelphia, PA.

We studied the impact of visual stimulation upon cerebral metabolism in normal young men using FDG-PET. Results obtained from subjects receiving patterned visual stimulation while performing an ocular fixation task were compared with results from ocular fixation alone. Visual stimulation in the macular region of either hemifield produced significant increases in metabolism of the contralateral posterior striate cortex. Visual stimulation induced highly significant asymmetries in metabolism of the prefrontal and inferior parietal cortices. Metabolic activation in extrastriate areas tended to be right-sided. These findings support the classic notion of retinotopic organization within the primary visual sensory cortex. They also indicate that the patterns of cerebral metabolism are not equivalent between the two cerebral hemispheres. This latter finding suggests that in humans the right cerebral hemisphere may be specialized for visual processing.

Address correspondence and reprint requests to Dr. Kushner, Cerebrovascular Research Center, Department of Neurology, 429 Johnson Pavilion, 36th and Hamilton Walk, University of Pennsylvania, Philadelphia, PA 19104.

Supported by Program Grant NS-14867-08 from the US Public Health Service. Dr. Kushner is the recipient of Clinical Investigation Development Award NS00999-02.

Received January 14, 1987. Accepted for publication in final form April 2, 1987.

This article has been cited by other articles:

				I. A. Romero, M.-C. Prevost, E. Perret, P. Adamson, J. Greenwood, P.-O. Couraud, and S. Ozden Interactions between Brain Endothelial Cells and Human T-Cell Leukemia Virus Type 1-Infected Lymphocytes: Mechanisms of Viral Entry into the Central Nervous System J. Virol., July 1, 2000; 74(13): 6021 - 6030. [Abstract] [Full Text]

				G. Panczel, M. Daffertshofer, S. Ries, D. Spiegel, and M. Hennerici Age and Stimulus Dependency of Visually Evoked Cerebral Blood Flow Responses Stroke, March 1, 1999; 30(3): 619 - 623. [Abstract] [Full Text] [PDF]

				M. Sturzenegger, D. W. Newell, and R. Aaslid Visually Evoked Blood Flow Response Assessed by Simultaneous Two-Channel Transcranial Doppler Using Flow Velocity Averaging Stroke, December 1, 1996; 27(12): 2256 - 2261. [Abstract] [Full Text]

				G. W. Hynd, M. Semrud-Clikeman, A. R. Lorys, E. S. Novey, D. Eliopulos, and H. Lyytinen Corpus Callosum Morphology in Attention Deficit-Hyperactivity Disorder: Morphometric Analysis of MRI J Learn Disabil, March 1, 1991; 24(3): 141 - 146. [Abstract] [PDF]