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NEUROLOGY 1988;38:352
© 1988 American Academy of Neurology

Neurologic disease in biopsy-proven giant cell (temporal) arteritis

Richard J. Caselli, MD, Gene G. Hunder, MD and Jack P. Whisnant, MD

From the Department of Neurology (Drs. Caselli and Whisnant) and Division of Rheumatology and Internal Medicine (Dr. Hunder), Mayo Clinic and Mayo Foundation, Rochester, MN.

Neurologic findings were studied in 166 consecutive patients with biopsy-proven giant cell (temporal) arteritis. Neurologic problems occurred in 51 patients (31%): neuropathies (23), TIA/strokes (12), neuro-otologic syndromes (11), tremor (6), neuropsychiatric syndromes (5), tongue numbness (3), and myelopathy (1). Neuro-ophthalmologic problems occurred in 35 patients (21%): amaurosis fugax (AF) (17), permanent vision loss (PVL) (14), scintillating scotoma (8), and diplopia (3). Abnormalities in large arteries in 52 patients (31%) included bruits and diminished pulses. The carotid artery was involved in 31 patients (bilateral in 58%). Overall, 35% of patients with carotid disease had TIA/stroke, AF, or PVL.

Address correspondence and reprint requests to Dr. Hunder, Mayo Clinic, 200 First Street SW, Rochester, MN 55905.

Presented in part at the thirty-eighth annual meeting of the American Academy of Neurology, New Orleans, LA, April 1986.

Received April 3, 1987. Accepted for publication in final form June 4, 1987.




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