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From the Neurological Clinic of the University of Sassari, Italy.
Prevalence studies carried out in Sardinia from 1975 suggest an increasing occurrence of MS. However, it is questionable whether this increase represents a real change in MS incidence or simply reflects longer survival. Data from 79 patients indicated the average annual incidence for the period 1965 through 1985 was 3. 4 per 100, 000. On December 31, 1985, the prevalence rate was 69 per 100, 000. Evaluation of MS temporal trends showed a significant increase in MS incidence during the study period: values ranged around two per 100, 000 in the triennial periods 1965–1967, 1968–1970, and 1971–1973, and around five in each triennium from 197-7 onward.
Address correspondence and reprint requests to Prof. Rosati, Clinica Neurologica Università, viale S. Pietro 10, 07100 Sassari, Italy.
Supported by the Assessorato Igiene e Sanita della Regione Autonoma della Sardegna and the Ministero della Pubblica Istruzione d'ltalia.
Presented in part at the International Symposium on Multiple Sclerosis, Rome, Italy, October 17–18, 1986.
Received January 20, 1987. Accepted for publication in final form June 12, 1987.
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