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From the Division of Neurology, Sinai Hospital of Baltimore, and the Johns Hopkins Epilepsy Center, Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD.
We studied the effect of seizures and myoclonus following cardiopulmonary resuscitation (CPR) on the outcome of all comatose adult survivors of CPR over an 8-year period. Either seizures or myoclonus occurred in 50 of 114 patients (44%): seizures in 41 patients (36%) and myoclonus in 40 (35%). Status epilepticus or status myoclonus occurred in 36 patients (32%), and 19 (17%) had myoclonic status epilepticus (MSE). Seizures and myoclonus per se were not significantly related to outcome, but status epilepticus, status myoclonus, and, particularly, MSE were predictive of poor outcome as judged by survival and recovery of consciousness.
Address correspondence and reprint requests to Dr. Krumholz, Division of Neurology, Sinai Hospital of Baltimore, Baltimore, MD 21215.
Presented in part at the thirty-sixth annual meeting of the American Academy of Neurology, Boston, MA, April 1984.
Received September 8, 1986. Accepted for publication in final form June 8, 1987.
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