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NEUROLOGY 1988;38:492
© 1988 American Academy of Neurology

Establishment of a CSF bank

R. E. Albright, Jr., MD, R. H. Christenson, PhD, S. C. Schold, Jr., MD, K. A. Schneider, MD, R. L. Habig, PhD, W. W. Johnston, MD, M. P. Pickett, MA, W. F. Kulik, Sr. and T. P. Mears, BSN

From the Departments of Medicine (Neurology) (Drs. Albright and Schold) and Pathology (Drs. Christenson, Schneider, Habig, and Johnston), Medical Center Information Systems (Mr. Pickett and Ms. Mears), and Medical Records (Mr. Kulik), Duke University Medical Center, Durham VA Medical Center, Durham, NC.

A bank of well-characterized CSF has been established by collecting and storing (— 70 °C) CSF samples remaining after completion of routine clinical studies. Over 1, 700 individual patient samples were collected during a 12-month period. A database derived largely from information downloaded from existing hospital-based systems includes the results of individual CSF laboratory studies, in addition to the patient age, primary diagnoses, and details of any malignancy. CSF control material is used to verify storage conditions. The CSF bank supplies investigators with CSF handled in a standardized manner for more precise investigation of CNS disease.

Address correspondence and reprint requests to Dr. Albright, Box 3963, Duke University Medical Center, Durham, NC 27710.

Supported in part by Veterans Administration grant 337-42-6008. Dr. Robert Albright is the recipient of an NINCDS Teacher Investigator Development Award 5K07-NS-01003.

Received June 11, 1987. Accepted for publication in final form July 13, 1987.






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