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From the Department of Neurology (Drs. Golbe and Duvoisin), University of Medicine and Dentistry of New Jersey - Robert Wood Johnson (formerly Rutgers) Medical School, New Brunswick, NJ; and the Neuroepidemiology Branch (Drs. Davis and Schoenberg), National Institutes of Neurological and Communicative Disorders and Stroke, Bethesda, MD.
We surveyed neurologists and chronic care facilities in and near two New Jersey counties with a combined population of 799,022, regarding cases of progressive supranuclear palsy. All suspected cases were examined personally, using rigid criteria. The prevalence ratio was 1.39/100,000. A total of 50 New Jersey cases yielded median intervals to onset of requiring gait assistance, 3.1 years; visual symptoms, 3.9 years; dysarthria, 3.4 years; dysphagia, 4.4 years; requiring wheelchair, 8.2 years; and death, 9.7 years.
Address correspondence and reprint requests to Dr. Golbe, Department of Neurology, UMDNJ-Robert Wood Johnson Medical School, CN-19, New Brunswick, NJ 08903.
Received June 3,1987. Accepted for publication in final form November 16,1987.
Presented in part at the thirty-ninth annual meeting of the American Academy of Neurology, New York, NY, April 1987.
*Deceased.
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