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NEUROLOGY 1988;38:1128
© 1988 American Academy of Neurology

A new case of Creutzfeldt-Jakob disease associated with human growth hormone therapy in New Zealand

M. Croxson, FRACP, P. Brown, MD, B. Synek, FRCPA, M. G. Harrington, MB, ChB, MRCP, R. Frith, FRACP, G. Clover, PhD, J. Wilson, FRACR and D. C. Gajdusek, MD

From Auckland Hospital (Drs. Croxson, Synek, Frith, Clover, and Wilson) Auckland, New Zealand; the Laboratory of CNS Studies (Drs. Brown and Gajdusek), NINCDS; and the Clinical Neurogenetics Branch (Dr. Harrington), NIMH, NIH, Bethesda, MD.

A clinically atypical, neuropathologically verified case of Creutzfeldt-Jakob disease is described in a 32-year-old New Zealand woman with idiopathic hypopituitarism who had been treated in late adolescence (1970 to 1973) with human growth hormone processed from pooled cadaveric pituitary glands.

Address correspondence and reprint requests to Dr. Brown, Building 36, Room 5B21, NINCDS, NIH, Bethesda, MD 20892.

Received September 2, 1987. Accepted for publication in final form November 25, 1987.




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