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Steroids after cardiac arrest

A retrospective study with concurrent, nonrandomized controls

Division of Neurology, Department of Medicine, University of Washington, Seattle, WA.

We retrospectively examined the effect of steroid treatment on the outcome of 458 consecutive patients admitted after out-of-hospital cardiac arrest. Of those given steroids, 128/213 (60%) regained consciousness, and of those not given steroids, 150/245 (61%) regained consciousness. Findings remained unchanged using logistic regression to adjust for differences in the two treatment groups. These results suggest that there is no role for steroids in the treatment of global brain ischemia.

Address correspondence and reprint requests to Dr. Longstreth, Division of Neurology, ZA-95, Harborview Medical Center, 325 9th Avenue, Seattle, WA 98104.

Received December 7, 1987. Accepted for publication in final form December 23, 1987.

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