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NEUROLOGY 1989;39:1386
© 1989 American Academy of Neurology

CNS chloromas in patients presenting with eosinophilia

John W. Henson, MD and Ronald G. Wiley, MD, PhD

Neurology Department, Vanderbilt University School of Medicine and VAMC, Nashville, TN.

A patient presented with hypereosinophilia for 3 years followed by acute leukemia with intracranial chloroma. Eight of 15 reported cases of myeloproliferative disorder accompanied by hypereosinophilia developed men-ingeal chloromas, suggesting a previously unrecognized association between eosinophilia, acute leukemia, and CNS chloroma.

Address correspondence and reprint requests to Dr. Wiley, Neurology Service (127), VAMC, 1310 24th Avenue, South, Nashville, TN 37212.

Supported by the Veterans Administration.

Received November 4, 1988. Accepted for publication in final form April 17, 1989.






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