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NEUROLOGY 1989;39:1572
© 1989 American Academy of Neurology

HTLV-I-associated myelopathy and polymyositis in a US native

B. K. Evans, MD, I. Gore, MD, L. E. Harrell, MD, T. Arnold, MD and S. J. Oh, MD

From the Departments of Neurology and Medicine, University of Alabama at Birmingham School of Medicine, and Birmingham Veterans Administration Medical Center. Birmingham, AL.

A patient who had always lived in the United States had an HTLV-I infection and a chronic myelopathy clinically mimicking amyotrophic lateral sclerosis. Needle EMG and nerve conduction studies were consistent with anterior horn cell disease but muscle biopsy showed denervation and an inflammatory myopathy. Serum HTLV-I antibody tests were positive and HTLV-I DNA was present in peripheral leukocytes. This is the 1st reported US native with HTLV-I-associated myelopathy and polymyositis.

Address correspondence and reprint requests to Dr. Evans, Department of Neurology, UAB Station, Birmingham, AL 35294.

Presented in part at the forty-first annual meeting of the American Academy of Neurology, Chicago, IL, April 1989.

Received March 28, 1989. Accepted for publication in final form June 2, 1989.




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