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Veterans Administration Medical Center, San Diego, and the Departments of Neurosciences, University of California, San Diego, CA (Dr. Kritchevsky)
Veterans Administration Medical Center, San Diego, and the Department of Psychiatry, University of California, San Diego, CA (Dr. Squire).
We gave six patients with transient global amnesia (TGA) neuropsychological tests during and after their episodes. During TGA, all patients had severe anterograde amnesia for verbal and nonverbal material and a patchy but temporally graded retrograde amnesia for personal and public events dating back to at least 1960. In addition, they were unusually passive during TGA, had impaired ability to copy a complex figure, and possibly had mild impairment of confrontation naming. All exhibited complete recovery of memory and other cognitive abilities after the episode. There are similarities between the transient amnesia of patients with TGA and the chronic amnesia of patients with presumed bilateral damage to the medial temporal region or the diencephalic midline.
Address correspondence and reprint requests to Dr. Kritchevsky, VA Supported by the Medical Research Service of the Veterans Administration, by NIMH grant MH24600, and by the Office of Naval Research.
Presented in part at the eighteenth annual meeting of the Society for Neuroscience, Toronto, November, 1988.
Medical Center (127), 3350 La Jolla Village Drive, San Diego, CA 92161.
Received June 6, 1988. Accepted for publication in final form August 8, 1988.
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