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NEUROLOGY 1989;39:602
© 1989 American Academy of Neurology

Dysplastic gangliocytoma and intractable partial seizures in childhood

Michael S. Duchowny, MD, Trevor J. Resnick, MD and Luis Alvarez, MD

Comprehensive Epilepsy Center and Department of Neurology. Miami Children's Hospital, and the Departments of Neurology and Pediatrics, University of Miami School of Medicine, Miami, FL.

We describe the clinical, radiologic, and EEG features of 3 children who had dysplastic gangliocytomas of the cerebral hemispheres and drug resistant partial seizures that began in infancy. Following cortical resection, 2 are seizure-free and the third almost seizure-free. The dysphasic gangliocytoma may be an important and surgically remediable cause of very early malignant partial seizures.

Address correspondence and reprint request to Dr. Duchowny, Comprehensive Epilepsy Center, Miami Children's Hospital, 6125 SW 31st Street, Miami, FL 33155.

Received August 24,1988. Accepted for publication in final form October 3,1988.




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