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NEUROLOGY 1989;39:1129
© 1989 American Academy of Neurology

HTLV-I-associated myelopathy with adult T-cell leukemia

H. Kawai, MD, Y. Nishida, MD, M. Takagi, MD, K. Nakamura, MD, K. Masuda, MD, S. Saito, MD and A. Shirakami, MD

First Department of Internal Medicine, School of Medicine, and School of Medical Sciences (Dr. Shirakami), The University of Tokushima, Tokushima, Japan.

We report a 42-year-old Japanese woman with HTLV-I-associated myelopathy (HAM) combined with adult T-cell leukemia (ATL). Combination of the 2 diseases has been extremely rare. The infrequency is explained by HLA types unique to each disease. Our patient suggests that the HAM-associated HLA haplotype does not prevent the development of ATL.

Address correspondence and reprint requests to Dr. Kawai, First Department of Internal Medicine, School of Medicine, The University of Tokushima, 3-Kuramoto, Tokushima 770, Japan.

Received January 10, 1989. Accepted for publication in final form March 3, 1989.




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