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NEUROLOGY 1989;39:1215
© 1989 American Academy of Neurology

Immunochromatographic measurement of phenobarbital in whole blood with a non-instrumented assay

B. Wannamaker, MD, L. Denio, BS, W. E. Dodson, MD, F. Dreifuss, MD, C. Crosby, RN, N. Santilli, RN, P. Duffner, MD, P. Ryan-Dudeck, RN, C. Conboy, RN, E. Ellis, MD, C. N. Ou, PhD, V. Frawley, MS, J. Ellis, MT, E. Vining, MD, J. Carrico, BS and S. Tillson, PhD

Epilepsy Services and Research Inc., Charleston, SC
Washington University, St. Louis, MO
University of Virginia Medical Center, Charlottesville, VA
Childrens Hospital, Buffalo, NY
Texas Children's Hospital, Houston, TX
Johns Hopkins Hospital, Baltimore, MD
Syva Company, Palo Alto, CA. L. Denio is now with the Department of Neurology, Ohio State University, Columbus, OH

We tested the precision and accuracy of the AccuLevel Phenobarbital Test, which reports whole-blood (fingerstick) results in plasma equivalent values, and compared these values with plasma results obtained using established methods. We conclude that the assay is precise, reliable, accurate for single tests, and is appropriate for use in offices, outpatient settings, and emergency rooms.

Address correspondence and reprint requests to Dr. Wannamaker, Epilepsy Services and Research Inc., 84 Halsey Boulevard, Charleston, SC 29401.

Presented in part at the thirty-eighth annual meeting of the American Academy of Neurology, New Orleans, LA, April 1986.

Received January 13, 1989. Accepted for publication in final form March 22, 1989.




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