HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Young, G. B. Articles by Zochodne, D. W. Search for Related Content PubMed PubMed Citation Articles by Young, G. B. Articles by Zochodne, D. W.

The significance of myoclonic status epilepticus in postanoxic coma

Departments of Clinical Neurological Sciences and Pathology, Victoria Hospital and the University of Western Ontario, London, ON, Canada.

We report 11 adults who exhibited myoclonic status epilepticus (MSE) after cardiac arrest. Based on pathologic, electroencephalographic, and clinical evidence, we conclude that our patients died from the initial anoxic-ischemic insult rather than as a result of MSE. We suggest that the seizures in these nonsurvivors were self-limited events arising from lethal damage to neurons. Thus, in patients with bilaterally synchronous facial myoclonus, bilateral loss of pupillary or oculovestibular reflexes, and suppression and burst-suppression on EEG, it is not warranted to use anesthetic barbiturates to treat MSE.

Address correspondence and reprint requests to Dr. G. Bryan Young, Department of Clinical Neurological Sciences, Victoria Hospital Corporation, Box 5375, London, ON, Canada, N6A 4G5.

Received February 12, 1990. Accepted for publication in final form May 14, 1990.

This article has been cited by other articles:

				D. J. Costello and A. J. Cole Treatment of Acute Seizures and Status Epilepticus J Intensive Care Med, November 1, 2007; 22(6): 319 - 347. [Abstract] [PDF]

				A. O. Rossetti, G. Logroscino, L. Liaudet, C. Ruffieux, V. Ribordy, M. D. Schaller, P. A. Despland, and M. Oddo Status epilepticus: An independent outcome predictor after cerebral anoxia Neurology, July 17, 2007; 69(3): 255 - 260. [Abstract] [Full Text] [PDF]

				E.F.M. Wijdicks, A. Hijdra, G. B. Young, C. L. Bassetti, and S. Wiebe Practice parameter: prediction of outcome in comatose survivors after cardiopulmonary resuscitation (an evidence-based review): report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology, July 25, 2006; 67(2): 203 - 210. [Abstract] [Full Text] [PDF]

				D. D. Bell, P. G. Brindley, D. Forrest, O. A. Muslim, and D. Zygun Management following resuscitation from cardiac arrest: recommendations from the 2003 Rocky Mountain Critical Care Conference: [Conduite a tenir apres la reanimation post-arret cardiaque : recommendations de la conference du Rocky Mountain Critical Care 2003] Can J Anesth, March 1, 2005; 52(3): 309 - 322. [Abstract] [Full Text] [PDF]

				A. Krumholz and A. T. Berg Further evidence that for status epilepticus ""one size fits all"" doesn't fit Neurology, February 26, 2002; 58(4): 515 - 516. [Full Text] [PDF]

				E. F. M. Wijdicks, N. G. Campeau, and G. M. Miller MR Imaging in Comatose Survivors of Cardiac Resuscitation AJNR Am. J. Neuroradiol., September 1, 2001; 22(8): 1561 - 1565. [Abstract] [Full Text] [PDF]

				O. Miyamoto and R. N. Auer Hypoxia, hyperoxia, ischemia, and brain necrosis Neurology, January 25, 2000; 54(2): 362 - 362. [Abstract] [Full Text] [PDF]