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Unit of Neurology (Drs. Dávalos, Cendra, Martinez, and Genís) and the Section of Neuroradiology (Dr. Teruel), Hospital of Girona, Girona, Spain.
To determine a risk profile of deterioration in cerebral infarction of less than 8 hours' duration, we studied prospectively a series of clinical and radiologic data in 98 patients. We evaluated the Canadian Neurological Scale Score and Barthel index during a follow-up period of 3 months. There was deterioration in the 1st 48 hours in 40.8% of the patients. High systolic blood pressure, elevated blood sugar concentration at admission, and carotid territory involvement were independently related with deterioration in the logistic regression analysis. Death occurred in 35% of the patients with deteriorating infarcts and in 8.6% of those with stable infarcts. At the end of the study, functional capacity was lower in those with deteriorating infarcts, but the 2 groups improved in parallel from the 4th day onward.
Address correspondence and reprint requests to Dr. Antoni Dávalos, Unit of Neurology, Hospital de Girona, Ctra de Francia s/n, 17007 Girona, Spain.
Received September 28, 1989. Accepted for publication in final form May 9, 1990.
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