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NEUROLOGY 1990;40:1894
© 1990 American Academy of Neurology

The utility and generality of Mini-Mental State Examination scores in Alzheimer's disease

B. Giordani, PhD, M. J. Boivin, PhD, A. L. Hall, BA, N. L. Foster, MD, S. J. Lehtinen, MA, L. A. Bluemlein, MS and S. Berent, PhD

Departments of Psychiatry (Drs. Giordani and Boivin, S.J. Lehtinen, and Dr. Berent), Psychology (Dr. Giordani, A.L. Hall, and Dr. Berent), and Neurology (Dr. Foster, L.A. Bluemlein, and Dr. Berent), University of Michigan, Ann Arbor, MI; and the Department of Psychology (Dr. Boivin), Spring Arbor College, Spring Arbor, MI.

The present study sought to evaluate the validity and generality of the Mini-Mental State Examination (MMSE) and its subsection scores. We gave the MMSE and other neuropsychological tests to 51 patients with probable Alzheimer's disease. On the basis of correlational and factor analyses, overall performance on the MMSE proved to have good concurrent validity with other comprehensive neuropsychological assessment instruments. However, the MMSE subsections should not be viewed as highly specific measures of cognition or memory.

Address correspondence and reprint requests to Dr. Bruno Giordani, Neuropsychology Program, Box 0840, Room 480, Med Inn Bldg., University of Michigan Medical Center, Ann Arbor, MI 48109-0840.

Received November 16, 1989. Accepted for publication in final form May 18, 1990.




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