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From the Department of Neurology (Drs. Zamrini, Meador, Loring, and Nichols), Surgery (Neurosurgery) (Dr. Lee), Radiology (Dr. Figueroa), and Office of Research Computing and Statistics (Dr. Thompson), Medical College of Georgia, and VA Medical Center (Dr. Zamrini). Augusta, GA.
We studied heart rate following unilateral hemispheric inactivation by intracarotid amobarbital in 25 patients undergoing preoperative evaluation for epilepsy surgery. Heart rate increased after left hemisphere inactivation, but decreased following right hemisphere inactivation. The results are consistent with differential left/right cerebral hemispheric effects on autonomic function, and appear related to functional and anatomic asymmetries in both the central and peripheral nervous systems.
Address correspondence and reprint requests to Dr. Edward Y. Zamrini, Section of Behavioral Neurology, Department of Neurology, Medical College of Georgia, Augusta, GA 30912.
Dr. Meador is recipient of NIH/NIA Clinical Investigator Award # 1K08 AG0031bt.
Received January 4, 1990. Accepted for publication in final form March 6, 1990.
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