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NEUROLOGY 1991;41:808
© 1991 American Academy of Neurology

Peripheral neuropathy in systemic lupus erythematosus

Roald Omdal, MD, Olaf A. Henriksen, MD, Svein Ivar Mellgren, MD and Gunnar Husby, MD

Departments of Rheumatology (Drs. Omdal and Husby) and Neurology (Drs. Henriksen and Mellgren), University Hospital, Tromso, Norway.

We studied 33 consecutive patients with systemic lupus erythematosus (SLE) for neuropathy by employing the Neuropathy Symptom Score (NSS), Neurological Disability Score (NDS), EMG and nerve conduction velocity (NCV) studies, and determinations of vibration thresholds (VT). Polyneuropathy defined as NCV abnormalities of two or more nerves occurred in seven patients (21%). Neuropathic symptoms showed a poor correlation with NCV and VT, while clinical neuropathic signs, VT, and NCV correlated with each other in most instances. When reporting frequencies of neuropathy in SLE, NCV studies should be used as a basis. NSS, NDS, and VT give additional quantifiable information and can be useful in the follow-up of patients and for evaluating the response to therapy.

Address correspondence and reprint requests to Dr. Roald Omdal, Department of Internal Medicine, Central Hospital, N-4011 Stavanger, Norway.

Dr. Omdal was supported as clinical research fellow by the Norwegian Research Council for Science and the Humanities.

Received July 19, 1990. Accepted for publication in final form November 2, 1990.




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