HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Correspondence: Submit a response Alert me when this article is cited Alert me when Correspondence are posted Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Sloan, M. A. Articles by Price, T. R. Search for Related Content PubMed PubMed Citation Articles by Sloan, M. A. Articles by Price, T. R.

Occurrence of stroke associated with use/abuse of drugs

Stroke Epidemiology Unit (Drs. Sloan, Kittner, and Price), Department of Neurology (Drs. Sloan, Kittner, and Price), Department of Epidemiology and Preventive Medicine (Drs. Kittner and Price), and Division of Neurological Surgery, Department of Surgery (Dr. Rigamonti), University of Maryland School of Medicine, Baltimore, MD.

Ischemic and hemorrhagic stroke frequently occur in temporal association with use or abuse of illicit and over-the-counter (OTC) sympathomimetic drugs. However, little information is available on the proportion of strokes associated with use/abuse of drugs in specific hospital populations. Between September 1, 1988, and August 1, 1989, 167 of 178 stroke patients entered into the Maryland Stroke Data Bank were asked for a history of drug use or abuse. Information was incomplete in 51 of 167 (31%) patients due to neurologic deficit or lack of inquiry. Eleven of the remaining 116 cases (9.5%) were historically associated with drug use. Age range was 25 to 56 years (mean, 41 years). Stroke associated with drug use occurred in four of 62 (6%) cerebral infarcts, two of 28 (7%) intracerebral hemorrhages, and five of 26 (19%) subarachnoid hemorrhages (p = ns). Drugs included cocaine in five (45%), OTC sympathomimetics in three (27%), phencyclidine in two (18%), and heroin in one (9%).

Address correspondence and reprint requests to Dr. Michael A. Sloan, Department of Neurology, University of Maryland Hospital, 22 So. Greene Street, Baltimore, MD 21201.

Supported by National Institute of Neurological Disorders and Stroke Grant NS 16332-07. Dr. Kittner is the recipient of a Clinical Investigator Development Award (K08-NS01319-01) from the National Institute of Neurological Disorders and Stroke, Bethesda, MD.

Presented in part at the 42nd annual meeting of the American Academy of Neurology, Miami Beach, FL, May 1990.

Received October 29, 1990. Accepted for publication in final form February 13, 1991.

This article has been cited by other articles:

				B R Thanvi and S D Treadwell Cannabis and stroke: is there a link? Postgrad. Med. J., February 1, 2009; 85(1000): 80 - 83. [Abstract] [Full Text] [PDF]

				C. Cantu, A. Arauz, L. M. Murillo-Bonilla, M. Lopez, and F. Barinagarrementeria Stroke Associated With Sympathomimetics Contained in Over-the-Counter Cough and Cold Drugs Stroke, July 1, 2003; 34(7): 1667 - 1672. [Abstract] [Full Text] [PDF]

				J. P. Broderick, C. M. Viscoli, T. Brott, W. N. Kernan, L. M. Brass, E. Feldmann, L. B. Morgenstern, J. L. Wilterdink, and R. I. Horwitz Major Risk Factors for Aneurysmal Subarachnoid Hemorrhage in the Young Are Modifiable Stroke, June 1, 2003; 34(6): 1375 - 1381. [Abstract] [Full Text] [PDF]

				L. B. Goldstein, R. Adams, K. Becker, C. D. Furberg, P. B. Gorelick, G. Hademenos, M. Hill, G. Howard, V. J. Howard, B. Jacobs, et al. Primary Prevention of Ischemic Stroke : A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association Circulation, January 2, 2001; 103(1): 163 - 182. [Full Text] [PDF]

				L. B. Goldstein, R. Adams, K. Becker, C. D. Furberg, P. B. Gorelick, G. Hademenos, M. Hill, G. Howard, V. J. Howard, B. Jacobs, et al. Primary Prevention of Ischemic Stroke : A Statement for Healthcare Professionals From the Stroke Council of the American Heart Association Stroke, January 1, 2001; 32(1): 280 - 299. [Full Text] [PDF]

				H. P. Adams Jr, L. J. Kappelle, J. Biller, D. L. Gordon, B. B. Love, F. Gomez, and M. Heffner Ischemic Stroke in Young Adults: Experience in 329 Patients Enrolled in the Iowa Registry of Stroke in Young Adults Arch Neurol, May 1, 1995; 52(5): 491 - 495. [Abstract] [PDF]

				J. F. Tapia and J. M. Schumacher Case 27-1993- A 32-Year-Old Man with the Sudden Onset of a Right-Sided Headache and Left Hemiplagia and Hemianesthesia N. Engl. J. Med., July 8, 1993; 329(2): 117 - 124. [Full Text]