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Magnetic resonance demonstration of intracranial CSF flow in children

Departments of Neurology and Radiology, University of Miami School of Medicine, Miami, FL.

We determined the feasibility and value of studying intracranial CSF flow in children with potential CSF pathway problems using a cardiac gated cine magnetic resonance (MR) format. We studied 15 consecutive patients with a variety of clinical problems that suggested possible CSF pathway problems. The diagnoses included Chiari malformation, Dandy-Walker syndrome, external hydrocephalus, cerebellar tumor, CNS histoplasmosis, and tuberculous meningitis. In addition to documenting the feasibility of the technique in children (7 of 15 were less than 2 years of age), we derived significant new information relative to pathogenesis and/or therapy. The study provides preliminary evidence supporting intracranial CSF flow studies at the time of routine MR imaging of appropriate children.

Address correspondence and reprint requests to Dr. Richard G. Curless, Department of Neurology, University of Miami School of Medicine, P.O. Box 016820, Mailman Center, D-820, Miami, FL 33101.

Received May 17, 1991. Accepted for publication in final form July 17, 1991.