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From the Neurologic Service (Drs. Del Brutto, Santibañez, Aguirre, Díaz, and Alarcon), Hospital Regional del Instituto Ecuatoriano de Seguridad Social, and the Department of Neurology (Dr. Noboa), Hospital Luis Vernaza, Guayaquil, Ecuador.
We reviewed clinical, EEG, and CT findings of 203 patients with epilepsy due to neurocysticercosis. Seizures were generalized in 121 patients and partial in 82. Thirty-two patients had focal signs and eight had papilledema. Eighty-one had generalized and 16 had focal EEG abnormalities. CT showed parenchymal brain calcifications in 53 patients and cysts in 150. There was an increased rate of focal signs in patients with single cysts as compared with patients with multiple cysts, and focal EEG abnormalities were present only in patients with single cysts. Fifty patients were lost to follow-up. The remaining 153 patients were followed for 28 ± 6 months; of these, 31 had calcifications and 122 had cysts. Anticonvulsants were started after the first visit in every patient. The 31 patients with calcifications remained free of seizures. Ninety-five of the 122 patients with cysts were also treated with anticysticercal drugs; of these, 79 (83%) had control of seizures. In contrast, only seven (26%) of 27 patients who did not receive anticysticercal drugs had control of seizures, indicating a strong correlation between the use of anticysticercal drugs and seizure control. Finally, of the 21 patients in whom anticonvulsants were withdrawn, 16 had relapses.
Address correspondence and reprint requests to Dr. Tomás A. Alarcón, Chief of Neurologic Service, Hospital Regional del I.E.S.S., PO Box 7308, Guayaquil, Ecuador.
Presented in part at the 43rd annual meeting of the American Academy of Neurology, Boston, MA, April 1991.
Received February 15, 1991. Accepted for publication in final form July 26, 1991.
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