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Department of Neurology, Kyoto University School of Medicine, Kyoto, Japan. (Drs. Kaji and Kimura)
Department of Brain Pathophysiology, Kyoto University School of Medicine, Kyoto, Japan. (Dr. Shibasaki)
We report two patients with multifocal demyelinating motor neuropathy whose symptoms improved after immunoglobulin infusion. Clinical signs included atrophy of the tongue and limb muscles, closely resembling that of motor neuron disease. Nerve conduction studies revealed multiple sites of motor conduction block without sensory abnormalities, suggesting selective involvement of motor fibers. Careful documentation of conduction block is required to diagnose this entity, which may be treated with immunoglobulin therapy.
Address correspondence and reprint requests to Dr. Ryuji Kaji, Department of Neurology, Kyoto University Hospital, Sakyoku, Kyoto 606, Japan.
Received June 11, 1991. Accepted for publication in final form August 27, 1991.
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