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NEUROLOGY 1992;42:516
© 1992 American Academy of Neurology

The frequency of selective IgA deficiency in myasthenia gravis

R. Liblau, MD, A-M. Fischer, MD, D. E. Shapiro, MS, E. Morel, PhD and J-F. Bach, MD, PhD

Department of Clinical Immunology, Necker Hospital, Paris, France (Drs. Liblau, Morel, and Bach)
Department Hematology, Necker Hospital, Paris, France (Dr. Fischer)
Department of Statistics, Stanford University, Stanford, CA. (D.E. Shapiro)

The frequency of selective IgA deficiency is unknown in myasthenia gravis. We screened a series of 333 consecutive adult myasthenic patients for selective IgA deficiency and found only one patient with a selective IgA deficiency, which is not significantly different from the normal population. Organ-specific autoimmune diseases may differ from systemic autoimmune diseases concerning their frequency of association with selective IgA deficiency.

Address correspondence and reprint requests to Dr. R. Liblau, Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA 94305.

Received June 19, 1991. Accepted for publication in final form August 26, 1991.







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