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NEUROLOGY 1992;42:642
© 1992 American Academy of Neurology

Simple partial seizures

Clinicofunctional correlation—A case report

S. Arroyo, MD, G. L. Krauss, MD, R. P. Lesser, MD, B. Gordon, MD, J. Hart, Jr., MD, B. S. Carson, MD and S. Uematsu, MD

Department of Neurology, The Johns Hopkins University School of Medicine, Baltimore, MD (Drs. Arroyo, Krauss, Lesser, Gordon, and Hart, Jr.)
Department of Neurosurgery, The Johns Hopkins University School of Medicine, Baltimore, MD (Drs. Lesser, Carson, and Uematsu)
The Zanvyl Krieger Mind/Brain Institute, The Johns Hopkins University, Baltimore, MD (Drs. Krauss, Lesser, Gordon, and Hart, Jr.).

A 12-year-old girl developed simple partial motor and sensory seizures due to a right perirolandic astrocytoma. Subdural EEG recording and functional stimulation disclosed close correlation between EEG-clinical manifestations of focal seizures and functional responses to cortical stimulation. This case supports the idea that responses in the perirolandic area to endogenous epileptogenic activity and to cortical stimulation reflect common underlying physiologic mechanisms.

Address correspondence and reprint requests to Dr. Santiago Arroyo, Department of Neurology, Meyer Building 2–147, The Johns Hopkins Hospital, 600 North Wolfe Street, Baltimore, MD 21205.

Supported in part by the National Institutes of Health (Grant no. 1 RO1 NS26553 from the National Institute of Neurological Disorders and Stroke), The Whittier Foundation, the Seaver Foundation, and the McDonnel-Pew Program in Cognitive Neuroscience. Dr. Arroyo was supported by a grant from the Fondo de Investigaciones Sanitarias, Spain.

Received July 10, 1991. Accepted for publication in final form August 26, 1991.






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