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Departments of Neurology, Heinrich-Heine University, Düsseldorf, Germany (Drs. Steinmetz, Kleinschmidt, and Schlaug, and J. Volkmann and Y. Huang)
Psychobiology and Psychocybernetics, Heinrich-Heine University, Düsseldorf, Germany (Dr. Jäncke).
We performed high-resolution magnetic resonance morphometry of the total midsagittal area and seven midsagittal subareas of the corpus callosum in healthy young adult dextrals and sinistrals (N = 52). There was no influence of handedness on these anatomic measurements. However, an effect of sex emerged, with women (N = 26) having a larger proportional isthmus segment of the callosum. This may reflect a sex-specific difference in the inter-hemispheric connectivity and functional organization of the temporoparietal association cortex.
Address correspondence and reprint requests to Dr. Helmuth Steinmetz, Department of Neurology, University Clinic, Heinrich-Heine University, Moorenstr. 5, W-4000 Düsseldorf 1, Federal Republic of Germany.
Supported by grants from the Deutsche Porschungsgemeinschaft (SFB 194/A7).
Received April 17, 1991. Accepted for publication in final form August 19, 1991.
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