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NEUROLOGY 1993;43:2508
© 1993 American Academy of Neurology

Neurophysiologic and clinical correlations of epileptic nystagmus

Peter W. Kaplan, MBBS, MRCP and Ronald J. Tusa, MD

Department of Neurology (Drs. Kaplan and Tusa), Johns Hopkins University School of Medicine; the Francis Scott Key Medical Center (Dr. Kaplan); and the Johns Hopkins Hospital (Drs. Kaplan and Tusa), Baltimore, MD.

Epileptic nystagmus (EN) is a rare sign of seizure activity. We describe eight patients with horizontal EN and hypothesize that the frequency of ictal discharge, anatomic localization of ictal activity, and level of consciousness determine its occurrence and mechanism. We believe that EN is due to epileptic activation of a cortical saccade region; in each case, quick phases were generated away from the side of the focus, and both quick and slow phases were totally confined to the field contraversive to the seizure focus.

Address correspondence and reprint requests to Dr. Peter W. Kaplan, Department of Neurology, FSKMC, 4940 Eastern Avenue, Baltimore, MD 21224.

Received February 25, 1993. Accepted for publication in final form May 11, 1993.




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