Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Logigian, E. L.
Right arrow Articles by Hollander, D.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Logigian, E. L.
Right arrow Articles by Hollander, D.
NEUROLOGY 1993;43:879
© 1993 American Academy of Neurology

Nonvasculitic, steroid-responsive mononeuritis multiplex

E. L. Logigian, MD, J. M. Shefner, MD, PhD, M. P. Frosch, MD, PhD, A. S. Kloman, MD, E. M. Raynor, MD, L. S. Adelman, MD and D. Hollander, MD

Departments of Neurology (Drs. Logigian, Shefner, and Raynor) and Pathology (Dr. Frosch), Brigham and Women's Hospital, Harvard Medical School; and the Departments of Neurology (Drs. Kloman and Hollander) and Pathology (Dr. Adelman), the New England Medical Center, Tufts University School of Medicine, Boston, MA.

We report two patients with mononeuritis multiplex, both of whom had focal inflammation of the perineurium and endoneurium on sural nerve biopsy without necrosis of blood vessel walls, histologic evidence of lymphoid malignancy, or mycobacterial infection. The predominant early sensory symptoms were asymmetric pain and paresthesias; subsequently, muscle weakness developed. Electrophysiologic studies showed an asymmetric sensorimotor axon loss radiculoneuropathy with denervation of limb and paraspinal muscles. Spinal fluid protein was elevated in one patient. There was no cause or underlying systemic disease. Marked improvement occurred with steroid therapy.

Address correspondence and reprint requests to Dr. D. Hollander, Department of Neurology, New England Medical Center, 750 Washington Street, Boston, MA 02111

Received April 1, 1992. Accepted for publication in final form September 29,1992.






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1993 by AAN Enterprises, Inc.