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High-dose intravenous immunoglobulin therapy in chronic progressive lumbosacral plexopathy

Department of Neurology, University of Miami School of Medicine, Miami, FL.

Previous reports of primary lumbosacral plexopathy (LSP) have stressed the benign nature of the syndrome. No effective treatment is known for the occasional patients who do not recover or who have relapses. We report two patients presenting with a progressive form of idiopathic LSP. Both patients showed remarkable improvement on high-dose intravenous immunoglobulin therapy. We suggest that these patients represent a treatable subgroup of LSP.

Address correspondence and reprint requests to Dr. W.G. Bradley, Department of Neurology (D4-5), P.O. Box 016960, University of Miami School of Medicine, Miami, FL 33101.

Received March 2, 1993. Accepted for publication in final form August 10,1993.

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