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Cognitive Neuroscience Laboratory, Department of Veterans Affairs Medical Center, and the University of California, San Francisce—Fresno-Central San Joaquin Valley Medical Education Program, Fresno, CA.
The contribution of cognitive slowing to the slowed performance of patients with Parkinson's disease (PD) is a matter of long-standing debate. In this study, we contrasted the performance of PD patients on two reaction-time tasks with the performance of Alzheimer's disease (AD) patients, young normal subjects, and elderly normal subjects. Both nondemented and demented PD patients showed cognitive as well as motor slowing, and the extent of cognitive slowing varied with overall cognitive status. Moreover, by comparison with the cognitive slowing in AD patients, cognitive slowing in PD patients was disproportionate to their general level of cognitive performance. We suggest that this disproportionality be used to differentiate the concepts of bradyphrenia and nonspecific cognitive slowing.
Address correspondence and reprint requests to Dr. Debra Sue Pate, Cognitive Neuroscience Laboratory (127), 2615 E. Clinton Avenue, Fresno, CA 93703.
Supported in part by the Office of Research and Development Medical Research Service of the Department of Veterans Affairs.
Presented a t the annual meeting of the Southern Society for Philosophy and Psychology, New Orleans, LA, April 1993.
Received February 5,1993. Accepted for publication in final form October 11,1993.
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