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Departments of Neurology and Internal Medicine and Institute for Social Sciences, Karl-Franzens University Graz, Austria.
Article abstract We administered the Mattis Dementia Rating Scale (MDRS) to 1,001 healthy volunteers, aged 50 to 80 years, randomly selected from our community. Multivariate regression analysis revealed educational level (p = 0.000004) and age (p = 0.00001), but no other sociodemographic or risk factors for stroke, to be significantly associated with the MDRS score. The age- and education-specific lowest quintile cutoff scores ranged from 140 in subjects aged 50 to 59 years with at least college experience to 130 in subjects aged 70 to 80 years with only 4 to 9 years of schooling. These percentile distributions obtained for decades of age and different levels of education should be useful reference values for clinicians and investigators when applying the MDRS to assess cognitive functioning.
Address correspondence and reprint requests to Dr. Reinhold Schmidt, Department of Neurology, Karl-Franzens University Graz, Auenbruggerplatz 22, A-8036 Graz, Austria.
Supported by Steiermärkische Krankenanstalten GmbH and the "Jubiläumsfond of the Austrian National Bank, Project #3905.
Presented in part at the 45th annual meeting of the American Academy of Neurology, New York, NY, April 1993.
Received August 10, 1993. Accepted for publication in final form October 26, 1993.
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