| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
Department of Neurology (Drs. Amato and Cornman), Wilford Hall Medical Center, Lackland AFB, TX, and the Department of Neurology (Dr. Kissel), The Ohio State University School of Medicine, Columbus, OH.
Stiff-man syndrome (SMS) is a rare disorder characterized by progressive rigidity, stiffness, and spasms of axial and extremity muscles. The etiology of SMS is unknown, but evidence suggests a possible autoimmune basis. The recent successful use of intravenous immunoglobulin (IVIG) in treating various autoimmune neuromuscular disorders led us to try IVIG in an uncontrolled pilot study on three patients. All three showed subjective and objective improvement.
Address correspondence and reprint requests to Dr. Anthony A. Amato, WHMC/PSMN, 2200 Bergquist Drive, Ste 1, Lackland AFB, TX 78236-5300.
Received November 5, 1993. Accepted in final form March 10, 1994.
This article has been cited by other articles:
|
|
 |
|
  G. Rakocevic, R. Raju, and M. C. Dalakas Anti-Glutamic Acid Decarboxylase Antibodies in the Serum and Cerebrospinal Fluid of Patients With Stiff-Person Syndrome: Correlation With Clinical Severity Arch Neurol, June 1, 2004; 61(6): 902 - 904. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Hassin-Baer, E. D. Kirson, L. Shulman, A. S. Buchman, H. Bin, M. Hindiyeh, L. Markevich, and E. Mendelson Stiff-Person Syndrome Following West Nile Fever Arch Neurol, June 1, 2004; 61(6): 938 - 941. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C M Wiles, P Brown, H Chapel, R Guerrini, R A C Hughes, T D Martin, P McCrone, J Newsom-Davis, J Palace, J H Rees, et al. Intravenous immunoglobulin in neurological disease: a specialist review J. Neurol. Neurosurg. Psychiatry, April 1, 2002; 72(4): 440 - 448. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. C. Dalakas, M. Fujii, M. Li, B. Lutfi, J. Kyhos, and B. McElroy High-Dose Intravenous Immune Globulin for Stiff-Person Syndrome N. Engl. J. Med., December 27, 2001; 345(26): 1870 - 1876. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. C. Dalakas, M. Li, M. Fujii, and D. M. Jacobowitz Stiff person syndrome: Quantification, specificity, and intrathecal synthesis of GAD65 antibodies Neurology, September 11, 2001; 57(5): 780 - 784. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H Takenoshita, M Shizuka-Ikeda, H Mitoma, S-Y Song, Y Harigaya, Y Igeta, M Yaguchi, K Ishida, M Shoji, M Tanaka, et al. Presynaptic inhibition of cerebellar GABAergic transmission by glutamate decarboxylase autoantibodies in progressive cerebellar ataxia J. Neurol. Neurosurg. Psychiatry, March 1, 2001; 70(3): 386 - 389. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A COLES, A COLES, and R BARKER A case of stiff limb syndrome responsive to plasma exchange J. Neurol. Neurosurg. Psychiatry, March 1, 2001; 70(3): 407a - 408. [Full Text]
|
|
|
|
|
|
M. C. Dalakas, M. Fujii, M. Li, and B. McElroy The clinical spectrum of anti-GAD antibody-positive patients with stiff-person syndrome Neurology, November 28, 2000; 55(10): 1531 - 1535. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Karussis and O. Abramsky Is the Routine Use of Intravenous Immunoglobulin Treatment in Neurologic Disorders Justified?: No Arch Neurol, August 1, 1999; 56(8): 1028 - 1032. [Full Text] [PDF]
|
|
|
|
|
|
M. Abele, M. Weller, S. Mescheriakov, K. Burk, J. Dichgans, and T. Klockgether Cerebellar ataxia with glutamic acid decarboxylase autoantibodies Neurology, March 1, 1999; 52(4): 857 - 857. [Abstract] [Full Text]
|
|
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
