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NEUROLOGY 1994;44:1697
© 1994 American Academy of Neurology

Rapid-rate transcranial magnetic stimulation and hemispheric language dominance

Usefulness and safety in epilepsy

R. Michelucci, MD, PhD, F. Valzania, MD, D. Passarelli, MD, M. Santangelo, MD, R. Rizzi, MD, A. M. Buzzi, MD, A. Tempestini, MD and C. A. Tassinari, MD

Department of Neurology, University of Bologna, Bellaria Hospital, Bologna, Italy.

We performed rapid-rate transcranial magnetic stimulation (r-TMS) in 14 epileptic patients, using a coil centered over nine different positions on each side of the scalp and while the subjects counted aloud. We obtained lateralized speech arrest, concordant with the site of manual preference, in only seven patients. There was transitory homonymous hemianopia (one patient), brief jerking of one arm (two patients), and affective (crying) reaction (three patients) after the end of a train of stimuli. In our experience, r-TMS is not as sensitive as previously reported for determination of hemispheric language dominance and may have undesirable side effects.

Address correspondence and reprint requests to Dr. Roberto Michelucci, Department of Neurology, Bellaria Hospital, Via Altura 3, 40139 Bologna, Italy.

Supported by the 40% funds distributed by the Italian Ministry of Education and CNR.

Received October 25, 1993. Accepted in final form March 1, 1994.




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