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NEUROLOGY 1995;45:30-33
© 1995 American Academy of Neurology

Assessment of MRI criteria for MS in Japanese MS and HAM/TSP

Y. Kuroda, MD, M. Matsui, MD, M. Yukitake, MD, K. Kurohara, MD, H. Takashima, MD, Y. Takashima, MD, C. Endo, MD, A. Kato, MD and F. Mihara, MD

Article abstract-We evaluated the usefulness of the MRI criteria for multiple sclerosis (MS) proposed by Paty et al and Fazekas et al in 36 Japanese MS patients, using HTLV-I-associated myelopathy (HAM)/tropical spastic paraparesis (TSP) as the control. Although 30 of 36 HAM/TSP patients had multiple white matter lesions on T2-weighted cranial MRI, only two fulfilled the MRI criteria for MS. At the same time, 31 of the 36 MS patients fulfilled the primary MRI criterion, yielding 93% specificity and 86% sensitivity for the criterion. MS has disease-specific MRI abnormalities.

NEUROLOGY 1995;45: 30-33




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