Neurology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Figures Only
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Correspondence:
Submit a response
Right arrow Alert me when this article is cited
Right arrow Alert me when Correspondence are posted
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Remy, P.
Right arrow Articles by Samson, Y.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Remy, P.
Right arrow Articles by Samson, Y.
NEUROLOGY 1995;45:472-477
© 1995 American Academy of Neurology

Peduncular 'Rubral' Tremor and Dopaminergic Denervation

A PET Study

P. Remy, MD, A. de Recondo, MD, G. Defer, MD, C. Loc'h, BS, P. Amarenco, MD, V. Plante-Bordeneuve, MD, M.-H. Dao-Castellana, MD, B. Bendriem, PhD, C. Crouzel, PhD, M. Clanet, MD, P. Rondot, MD and Y. Samson, MD

Article abstract-Lesions causing so-called rubral tremors frequently involve the substantia nigra or the nigrostriatal fibers, suggesting dopaminergic denervation as possibly contributory. We examined this hypothesis using PET and (Fluorine-18)-fluorodopa in six patients with a contralateral tremor following a peduncular lesion. The denervation revealed by PET was even more marked than in severe parkinsonian patients. All patients showed partial to complete improvement with levodopa therapy. PET evaluation of D2-receptors with (Bromine-76)bromolisuride showed no asymmetry of the D2 binding despite the important asymmetry of Fluorine-18-fluorodopa uptake. Our results indicate an important involvement of the nigral dopaminergic system in peduncular tremors that appears to be independent of postsynaptic dopamine receptors.

NEUROLOGY 1995;45: 472-477




This article has been cited by other articles:


Home page
 J. Neurol. Neurosurg. PsychiatryHome page
S Seidel, G Kasprian, F Leutmezer, D Prayer, and E Auff
Disruption of nigrostriatal and cerebellothalamic pathways in dopamine responsive Holmes' tremor
J. Neurol. Neurosurg. Psychiatry, August 1, 2009; 80(8): 921 - 923.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
J C M Zijlmans, R Katzenschlager, S E Daniel, and A J L Lees
The L-dopa response in vascular parkinsonism
J. Neurol. Neurosurg. Psychiatry, April 1, 2004; 75(4): 545 - 547.
[Abstract] [Full Text] [PDF]

Home page
 J. Neurol. Neurosurg. PsychiatryHome page
M-C Kim, B C Son, Y Miyagi, and J-K Kang
Vim thalamotomy for Holmes' tremor secondary to midbrain tumour
J. Neurol. Neurosurg. Psychiatry, October 1, 2002; 73(4): 453 - 455.
[Abstract] [Full Text] [PDF]

Home page
 Arch NeurolHome page
M.-J. Ribeiro, M. Vidailhet, C. Loc'h, C. Dupel, J. P. Nguyen, M. Ponchant, F. Dolle, M. Peschanski, P. Hantraye, P. Cesaro, et al.
Dopaminergic Function and Dopamine Transporter Binding Assessed With Positron Emission Tomography in Parkinson Disease
Arch Neurol, April 1, 2002; 59(4): 580 - 586.
[Abstract] [Full Text] [PDF]

Home page
 BrainHome page
S. H. Alusi, J. Worthington, S. Glickman, and P. G. Bain
A study of tremor in multiple sclerosis
Brain, April 1, 2001; 124(4): 720 - 730.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1995 by AAN Enterprises, Inc.