Neurology, Vol 45, Issue 7 1294-1296, Copyright © 1995 by American Academy of Neurology

ARTICLES

Trigeminal neuralgia in multiple sclerosis

JP Hooge and WK Redekop
Department of Medicine, University of British Columbia, Vancouver, Canada.

Trigeminal neuralgia (TN) occurred in 35 patients (1.9%) from a large multiple sclerosis (MS) clinic population (N = 1,882). TN began on average 11.8 years after the first MS symptom but in five patients was the first symptom of MS, preceding the next MS symptom by 1 to 11 years. The onset of MS was later in the patients who had TN, and bilateral TN occurred more frequently than expected (in 14% of TN patients). The age at onset of TN was no younger than in idiopathic TN except when TN was the first MS symptom. Most patients had a good result from medical or surgical therapy.

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