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NEUROLOGY 1996;46:385-387
© 1996 American Academy of Neurology

Comparison between multiple sclerosis in India and the United States

A case-control study

S. Bansil, MD, B. S. Singhal, MD, G. K. Ahuja, MD, U. Ladiwala, MD, M. Behari, MD, R. Friede, BA and S. D. Cook, MD

From the Department of Neurosciences (Drs. Bansil, Friede, and Cook), University of Medicine and Dentistry of New Jersey, New Jersey Medical School Newark, NJ; the Department of Neurology (Drs. Singhal and Ladiwala), Bombay Hospital Bombay, India; and the Neuro-Sciences Centre (Drs. Ahuja and Behari), All India Institute of Medical Sciences, New Delhi, India.
Received January 10, 1995. Accepted in final form June 21. 1995.
Address correspondence and reprint requests to Dr. Shalini Bansil, University of Medicine and Dentistry of New Jersey, 185 South Orange Avenue, MSB-H-506, Newark, NJ 07103.

The prevalence of MS in India is low, and it is unclear whether the manifestations of the disease in India are similar to the United States.We carried out a case-control study to compare the disease in the two populations and used clinical, evoked potential, and MRI criteria to assess similarities and differences. Our results indicate that the rate of disease progression and frequency of involvement of the cerebral hemispheres, cerebellum, spinal cord, and brainstem were similar in the two populations. The visual system was more frequently involved in Indian patients. No Indian patient had a family history of MS, this suggests an environmental disease-triggering agent.

NEUROLOGY 1996;46: 385-387




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