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Brueghel syndrome

Its distinction from Meige syndrome

From the Department of Physiology and Biophysics, University of South Florida, Tampa, FL.
Received June 21, 1995. Accepted in final form September 25, 1995.
Address correspondence and reprint requests to Dr. Gordon J. Gilbert, 500 Pasadena Avenue South, St. Petersburg, FL 33707.

A critical historical evaluation of the cranial dystonias supports the separation of the dystonia of the motor trigeminal nerve producing a widely opened mouth (Brueghel syndrome) from the more common facial dystonias with blepharospasm (Meige syndrome).In a patient with Brueghel syndrome, paroxysmal hyperpnea coincided with dystonic gaping; the finding of upbeating nystagmus suggests pontine localization in the pathogenesis of this rare disorder.

NEUROLOGY 1996;46: 1767-1769

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