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NEUROLOGY 1996;47:264-265
© 1996 American Academy of Neurology

Accuracy of reported family histories of essential tremor

K. Busenbark, BSN, P. Barnes, BA, K. Lyons, PhD, D. Ince, MD, F. Villagra, PhD and W. C. Koller, MD, PhD

From the Department of Neurology, University of Kansas Medical Center, Kansas City, KS (K. Busenbark, P. Barnes, Drs. Lyons, Villagra, and Koller) and the Department of Neurology, Marmara University Hospital, Istanbul, Turkey (Dr. Ince).
Received August 31, 1995. Accepted in final form October 4, 1995.
Address correspondence and reprint requests to Karen Busenbark, Department of Neurology, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160-7314.

We studied the accuracy of reported family histories of essential tremor (ET) by questioning the patients in our clinic and subsequently by mail and phone.For individuals who continued to report a negative family history, we mailed a screening questionnaire to their first-degree relatives to further ascertain the presence of ET. On initial assessment, 67.7% of patients reported a positive family history of ET, but following all assessments, 96.0% of patients had a positive family history. We conclude that a negative family history of ET is often inaccurate, and that ET is primarily a hereditary disease.

NEUROLOGY 1996;47: 264-265




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