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Mechanical ventilation in stroke patients--is it worthwhile?

From the Department of Neurology, Elias Sourasky Medical Center and Sackler Faculty of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Received April 28, 1994. Accepted in final form March 13, 1996.
Address correspondence and reprint requests to Dr. Amos D. Korczyn, Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv 69978, Israel.

We assessed the therapeutic efficacy and outcome of mechanical ventilation (MV) in patients with acute respiratory failure (ARF) following ischemic stroke (IS) or intracerebral hemorrhage (ICH), retrospectively graded by patients with IS (n = 881) and ICH (n = 108) admitted to our service during 11 years, according to the severity of their clinical state and to whether we employed MV.Outcome was recorded in terms of survival and duration of MV and compared with patients with neuromuscular (NM) diseases. We found a very high in-hospital mortality in stroke patients who were treated with ventilation (90.5% for IS and 87.5% for ICH) compared with NM patients (29%). We conclude that MV in stroke patients with ARF is not life-saving, and its use should be considered only after considering other potentially important factors.

NEUROLOGY 1996;47: 657-659

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